Urgent Relief Needed for Severe, Acute IBS Pain:
The Silent Epidemic

IBS affects 6-12% of the U.S. population, disrupting daily life with recurrent, severe pain episodes. Yet, despite its impact:

❌ No FDA-approved medication exists for svere, acute IBS pain

❌ Pain episodes last for hours, occurring multiple times a week

❌ 20% of IBS patients resort to opioids, worsening gut symptoms

ROSE-010 is the first and only fast-acting GLP-1 therapy designed for on-demand IBS pain relief.

Understanding IBS & the Pain Crisis

IBS is a gut-brain interaction disorder characterized by:

  • Abdominal pain associated with abnormal bowel habits
  • Subtypes: IBS with Constipation (IBS-C), IBS with Diarrhea (IBS-D), or Mixed Type (IBS-M)
  • Moderate to severe IBS can drastically reduce quality of life

What Makes IBS Pain Different?
  • Many patients experience severe, intermittent pain attacks that can last for hours
  • The pain occurs suddenly, often above any background discomfort
  • 20% of IBS patients rely on opioids, despite limited effectiveness and worsening motility symptoms.